X連鎖α-地中海貧血／精神發(fā)育遲滯（又叫ATR-X綜合征）是一種X連鎖遺傳的精神發(fā)育遲滯綜合征。大約有一半的患者已發(fā)現(xiàn)有ATRX基因突變。轉(zhuǎn)錄調(diào)節(jié)因子ATRX也稱為ATP依賴性解旋酶ATRX。X連鎖核蛋白（XNP）或X連鎖解旋酶II是由ATRX編碼的蛋白質(zhì)。ATRX基因的突變與X連鎖精神發(fā)育遲滯（XLMR）綜合征相關(guān)，常伴有α-地中海貧血（ATRX）綜合征。
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產(chǎn)品詳情：
類型：多克隆抗體
來源：Rabbit IgG
應(yīng)用：?IHC,WB,ICC-IF
反應(yīng)種屬：human
免疫原：Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: AAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRR
緩沖液組成：40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative
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應(yīng)用實(shí)例：
Immunohistochemical staining of human uterine cervix shows moderate to strong nuclear positivity in sequamous epithelial cells.
WB analysis in A549 cells transfected with control siRNA, target specific siRNA probe#1 and #2, using anti-ATRX antibody. Remaining relative intensity is presented. Loading control:anti-GAPDH.
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mmunofluorescent staining of human cell line A549 shows localization to nucleoplasm and nuclear bodies. Antibody staining is shown in green.
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訂購信息：
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