HNF1B基因位于17號(hào)染色體,含有9個(gè)外顯子,編碼肝細(xì)胞核因子1β(hepatocyte nuclear factor 1β,HNF1β)。HNF1β為含有同源結(jié)構(gòu)域的轉(zhuǎn)錄因子超家族中的一員,在胰腺、腎臟、腸道、肝臟、生殖道等多種器官起著重要的組織特異性調(diào)控基因表達(dá)的作用,同時(shí)也參與了這些器官的胚胎發(fā)育。
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產(chǎn)品詳情:
別名:HNF1beta, LFB3, MODY5, TCF2, VHNF1
類(lèi)型:多克隆抗體
來(lái)源:Rabbit IgG
應(yīng)用:?IHC,WB,ICC-IF
反應(yīng)種屬:human
免疫原:Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KEVLVQALEELLPSPNFGVKLETLPLSPGSGAEPDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQH
緩沖液組成:40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
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應(yīng)用實(shí)例:
Immunohistochemical staining of human renal?cancer shows moderate to strong nuclear positivity in tumorl cells.
WB analysis in human?kidney tissue.
Immunofluorescent staining of human cell line CACO-2?shows localization to nucleoplasm. Antibody staining is shown in green.
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訂購(gòu)信息:
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