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Endothelin-1 ELISA kit——ENZO熱銷產(chǎn)品

2023-09-01
瀏覽次數(shù): 16

靈敏、快速的內(nèi)皮素-1 ELISA試劑盒,適用于心血管和應(yīng)激相關(guān)研究

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內(nèi)皮素(Endothelin, ET)是由血管內(nèi)皮細(xì)胞產(chǎn)生的異肽,具有強(qiáng)大的血管收縮活性。這種肽由三個(gè)獨(dú)立的基因編碼,經(jīng)過(guò)加工產(chǎn)生39個(gè)殘基的 '大ET '分子,再進(jìn)一步加工成21個(gè)氨基酸序列,命名為ET-1、ET-2和ET-3。ET的作用是通過(guò)與兩個(gè)受體(ETA和ETB)的結(jié)合來(lái)介導(dǎo)的。ETA的激活會(huì)增加血管收縮和鈉潴留,從而增加血壓。ETB受體的激活引發(fā)血管舒張因子的釋放,如內(nèi)皮細(xì)胞的一氧化氮(NO)和前列腺素,并增加尿液的產(chǎn)生和排出,從而降低血壓。

欣博盛生物作為Enzo Life Sciences授權(quán)中國(guó)一級(jí)代理,可提供該產(chǎn)品,歡迎咨詢。

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產(chǎn)品特點(diǎn)

◆ 高靈敏度,可檢測(cè)低至0.41pg/ml的ET-1,正常和病理樣本均可檢測(cè)

◆ 高通量,僅需2小時(shí)就能得到38份樣本(含復(fù)孔)的檢測(cè)結(jié)果

◆ 可靈活選擇過(guò)夜或1小時(shí)孵育

◆ 適用于多種樣本類型

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產(chǎn)品信息

產(chǎn)品貨號(hào)

ADI-900-020A

產(chǎn)品名稱

Endothelin-1 ELISA kit(內(nèi)皮素-1 ELISA試劑盒)

規(guī)格

96 wells

靈敏度

0.41 pg/ml

檢測(cè)范圍

0.78 - 100 pg/ml

應(yīng)用

ELISA, Colorimetric detection

適用樣本類型

For the quantitative determination of ET-1 in culture supernatants, plasma,?

and serum of human, mouse, rat, cow, dog, pig, and rabbit origin.?

Cited sample types include cell lysates and tissue homogenates.

檢測(cè)波長(zhǎng)

450 nm

適用種屬

Human, Mouse, Rat

Bovine, Dog, Porcine, Rabbit

運(yùn)輸

Blue Ice Not Frozen

長(zhǎng)期保存

+4°C

試劑盒組分

Microtiter plate, Antibody diluent, Antibody concentrate, Assay buffer 17,?

Wash buffer concentrate, Standard, TMB Substrate, Stop solution 2

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標(biāo)準(zhǔn)曲線示例

Endothelin-1 ELISA kit——ENZO熱銷產(chǎn)品

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部分產(chǎn)品引用文獻(xiàn)

1.?NiONPs-induced alteration in calcium signaling and mitochondrial function in pulmonary artery endothelial cells involves oxidative stress and TRPV4 channels disruption: O. Germande, et al.; Nanotoxicology 16, 29 (2022)

2.?Treatment with apocynin selectively restores hippocampal arteriole function and seizure-induced hyperemia in a model of preeclampsia: M.J. Cipolla, et al.; J. Cereb. Blood Flow Metab. (2022)

3.?Vasorin plays a critical role in vascular smooth muscle cells and arterial function: L. Louvet, et al.; J. Cell. Physiol. 237, 3845 (2022)

4.?Contributions of Sodium-Hydrogen Exchanger-1 and Mitogen-Activated Protein Kinases to Enhanced Retinal Venular Constriction to Endothelin-1 in Diabetes: Y.L. Chen, et al.; Diabetes 70, 2353 (2021)

5.?Dehulled Adlay Consumption Modulates Blood Pressure in Spontaneously Hypertensive Rats and Overweight and Obese Young Adults: W.-J. Jeh, et al.; Nutrients 13, 2305 (2021)

6.?Estrogen modulates metabolic risk profile after resistance training in early postmenopausal women: a randomized controlled trial: T.V. Dam, et al.; Menopause 28, 1214 (2021)

7.?Impaired pulmonary vasomotor control in exercising swine with multiple comorbidities: J. van de Wouw, et al.; Basic Res. Cardiol. 116, 51 (2021)

8.?Anthocyanin-Rich New Zealand Blackcurrant Extract Supports the Maintenance of Forearm Blood-Flow During Prolonged Sedentary Sitting: M.J. Barnes, et al.; Front. Nutr. 7, 74 (2020)

9.?Aerobic exercise training improves insulin-induced vasorelaxation in a vessel-specific manner in rats with insulin-treated experimental diabetes: M.W. McDonald, et al.; Diab. Vasc. Dis. Res. 16, 77 (2019)

10.?Chronic consumption of a low calorie, high polyphenol cranberry beverage attenuates inflammation and improves glucoregulation and HDL cholesterol in healthy overweight humans: a randomized controlled trial: B. Chew, et al.; Eur. J. Nutr. 58, 1223 (2019)

11.?Gelatin-based perfusable, endothelial carotid artery model for the study of atherosclerosis: R. Chen, et al.; Biomed. Eng. Online 18, 87 (2019)

12.?Hyperglycemia enhances constriction of retinal venules via activation of the reverse-mode sodium-calcium exchanger: Y.L. Chen, et al.; Diabetes 68, 1624 (2019)

13.?In Vivo Comparative Study on Acute and Sub-acute Biological Effects Induced by Ultrafine Particles of Different Anthropogenic Sources in BALB/c Mice: F. Farina, et al.; Int. J. Mol. Sci. 20, 2805 (2019)

14.?Co-ingestion of whole eggs or egg whites with glucose protects against postprandial hyperglycaemia-induced oxidative stress and dysregulated arginine metabolism in association with improved vascular endothelial function in prediabetic men: J.D. McDonald, et al.; Br. J. Nutr. 120, 901 (2018)

15.?Effects of Personal Short-Term Exposure to Ambient Ozone on Blood Pressure and Vascular Endothelial Function: A Mechanistic Study Based on DNA Methylation and Metabolomics: Y. Xia, et al.; Environ. Sci. Technol. 52, 12774 (2018)

16.?Andrographolide inhibits hypoxia-induced HIF-1α-driven endothelin 1 secretion by activating Nrf2/HO-1 and promoting the expression of prolyl hydroxylases 2/3 in human endothelial cells: H.C. Lin, et al.; Environ. Toxicol. 32, 918 (2017)

17.?Renoprotective effects of montelukast in an experimental model of cisplatin nephrotoxicity in rats: A.M. Gad, et al.; J. Biochem. Mol. Toxicol. 31, (2017)

18.?Cardiac volume overload and pulmonary hypertension in long-term follow-up of patients with a transjugular intrahepatic portosystemic shunt: A. Wannhoff, et al.; Aliment. Pharmacol. Ther. 43, 955 (2016)

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Endothelin-1 ELISA kit——ENZO熱銷產(chǎn)品

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