品牌：Mabtech?
中文名稱(chēng)：猴IFN-γ酶聯(lián)免疫斑點(diǎn)檢測(cè)試劑盒
貨號(hào)：3421M-4AST
應(yīng)用：ELISpot
反應(yīng)種屬：小鼠
組分：Biotinylated detection mAb (7-B6-1)
Streptavidin-ALP
anti-CD3 mAb
Substrate (BCIP/NBT-plus)
2 Pre-coated strip clear plates (mAb MT126L)
規(guī)格：2 plates，10 plates
IFN-γ：干擾素-γ (IFN-γ, 也稱(chēng) IFN-gamma, IFN-g和Interferon-gamma)主要由活化的T細(xì)胞和NK細(xì)胞產(chǎn)生。它是一種激活巨噬細(xì)胞和內(nèi)皮細(xì)胞的促炎細(xì)胞因子，也通過(guò)影響APC、T和B細(xì)胞來(lái)調(diào)節(jié)免疫反應(yīng)。輔助T細(xì)胞和細(xì)胞毒性T細(xì)胞產(chǎn)生IF ELISpot N-γ是th1型表型的標(biāo)志，因此，大量IFN-γ的產(chǎn)生通常與宿主對(duì)胞內(nèi)病原體的有效防御有關(guān)。
參考文獻(xiàn)：
Roques, P., et al. (2017). Attenuated and vectored vaccines protect nonhuman primates against Chikungunya virus. JCI Insight.
Sauermann, U., et al. (2017). Vector order determines protection against pathogenic simian immunodeficiency virus infection in a triple component vaccine by balancing CD4 and CD8 T-cell responses. Journal of virology.
Sharpe, S. A., et al. (2018). Refinement and reduction through application of a quantitative score system for estimation of TB-induced disease burden using computed tomography. Lab Anim.
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