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腸道菌群

2021-05-17
瀏覽次數(shù)： 102
人體內(nèi)的細(xì)菌數(shù)量是人體細(xì)胞的10倍。這些微生物群廣泛存在腸道上皮和粘膜細(xì)胞表面，對維持機體健康起著非常重要的作用。如果正常的共生微生物群（腸道菌群）的生態(tài)平衡發(fā)生紊亂，將嚴(yán)重影響人體健康，引發(fā)風(fēng)濕性關(guān)節(jié)炎、炎癥性腸病、多發(fā)性硬化癥及糖尿病等多種疾病。除了能抵御有害病菌造成的物理及化學(xué)的傷害，腸道菌群在維持免疫功能(Th17，Treg及固有淋巴細(xì)胞)方面也發(fā)揮著重要的作用。
腸道免疫系統(tǒng)能區(qū)分共生菌和病原菌，對共生菌產(chǎn)生免疫耐受，而對病原菌及其他抗原物質(zhì)產(chǎn)生免疫反應(yīng)。Th17細(xì)胞是能產(chǎn)生IL-17的CD4+T淋巴細(xì)胞亞群，Th17的產(chǎn)生依賴于腸道共生菌的存在，并成為腸道免疫屏障的重要組成部分。它的適量存在有助于維持腸道免疫功能，而Th17的過度誘導(dǎo)則會導(dǎo)致腸道免疫功能破壞。此外，在腸道免疫系統(tǒng)中對共生菌耐受的CD4+CD25+Treg細(xì)胞及其產(chǎn)生的一致性細(xì)胞因子IL-10和TGF-β也發(fā)揮著重要作用，Th17細(xì)胞的分化發(fā)育又與Treg細(xì)胞分化發(fā)育呈抑制性關(guān)系。因此，Th17和Treg細(xì)胞是連接著腸道菌群和腸道免疫功能的關(guān)鍵細(xì)胞亞群。
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產(chǎn)品信息
?產(chǎn)品名稱
?產(chǎn)品編號
?克隆號
?應(yīng)用
?Anti-Mouse?AHR?Alexa?Fluor??488
?53-5925
?4MEJJ
?FC
?Anti-Mouse?AHR?eFluor??660
?50-5925
?4MEJJ
?FC
?Anti-Mouse?AHR?PE
?12-5925
?4MEJJ
?FC
?Anti-Human?AHR?eFluor??660
?50-9854
?FF3399
?FC
?Anti-Human?AHR?PE
?12-9854
?FF3399
?FC
?Anti-Human?AHR?PerCP-eFluor??710
?46-9854
?FF3399
?FC
?Anti-Human?AHR?Purified
?14-9854
?FF3399
?FC,?ICC,?IHC,?WB
?Anti-Mouse?Aiolos?eFluor??660
?50-5789
?8B2
?FC
?Anti-Mouse?Aiolos?PE
?12-5789
?8B2
?FC
?Anti-Mouse?Aiolos?Purified
?14-5789
?8B2
?WB
?Anti-Human?Foxp3?PE-Cyanine7
?25-4776
?PCH101
?FC
?Anti-Human/Mouse?c-Maf?eFluor??660
?50-9855
?sym0F1
?FC
?Anti-Human/Mouse?c-Maf?PerCP-eFluor??710
?46-9855
?sym0F1
?FC
?Anti-Human?CCL5?(RANTES)?eFluor??660
?50-9905
?VL1
?FC
?Anti-Mouse?CD4?Alexa?Fluor??488
?53-0041
?GK1.5
?FC
?Anti-Mouse?CD4?APC
?17-0041
?GK1.5
?FC
?Anti-Mouse?CD4?APC-eFluor??780
?47-0041
?GK1.5
?FC
?Anti-Mouse?CD4?Biotin
?13-0041
?GK1.5
?FC
?Anti-Mouse?CD4?Cyanine5
?19-0041
?GK1.5
?FC
?Anti-Mouse?CD4?eFluor??450
?48-0041
?GK1.5
?FC
?Anti-Mouse?CD4?eFluor??605NC
?93-0041
?GK1.5
?FC
?Anti-Mouse?CD4?eFluor??650NC
?95-0041
?GK1.5
?FC
?Anti-Mouse?CD4?eFluor??660
?50-0041
?GK1.5
?FC
?Anti-Mouse?CD4?FITC
?11-0041
?GK1.5
?FC
?Anti-Mouse?CD4?Functional?Grade?Purified
?16-0041
?GK1.5
?FC,?FA
?Anti-Mouse?CD4?PE
?12-0041
?GK1.5
?FC
?Anti-Mouse?CD4?PE-Cyanine5
?15-0041
?GK1.5
?FC
?Anti-Mouse?CD4?PE-Cyanine7
?25-0041
?GK1.5
?FC
?Anti-Mouse?CD4?PerCP-eFluor??710
?46-0041
?GK1.5
?FC
?Anti-Mouse?CD4?Purified
?14-0041
?GK1.5
?FC,?IHC,?IP
?Anti-Human?CD4?Alexa?Fluor??488
?53-0048
?OKT4?(OKT-4)
?FC
?Anti-Human?CD4?APC
?17-0048
?OKT4?(OKT-4)
?FC
?Anti-Human?CD4?APC-eFluor??780
?47-0048
?OKT4?(OKT-4)
?FC
?Anti-Human?CD4?Biotin
?13-0048
?OKT4?(OKT-4)
?FC
?Anti-Human?CD4?eFluor??450
?48-0048
?OKT4?(OKT-4)
?FC
?Anti-Human?CD4?eFluor??605NC
?93-0048
?OKT4?(OKT-4)
?FC
?Anti-Human?CD4?eFluor??660
?50-0048
?OKT4?(OKT-4)
?FC
?Anti-Human?CD4?FITC
?11-0048
?OKT4?(OKT-4)
?FC
?Anti-Human?CD4?Functional?Grade?Purified
?16-0048
?OKT4?(OKT-4)
?FC,?IP
?Anti-Human?CD4?PE
?12-0048
?OKT4?(OKT-4)
?FC
?Anti-Human?CD4?PerCP-Cyanine5.5
?45-0048
?OKT4?(OKT-4)
?FC
?Anti-Human?CD4?Purified
?14-0048
?OKT4?(OKT-4)
?FC,?IP
?Anti-Rat?CD4?APC
?17-0040
?OX35
?FC
?Anti-Rat?CD4?FITC
?11-0040
?OX35
?FC
?Anti-Rat?CD4?PE
?12-0040
?OX35
?FC
?Anti-Rat?CD4?PerCP-eFluor??710
?46-0040
?OX35
?FC
?Anti-Rat?CD4?Purified
?14-0040
?OX35
?FC,?IHC
?Anti-Mouse?CD4?Biotin
?13-0043
?RM4-4
?FC
?Anti-Mouse?CD4?FITC
?11-0043
?RM4-4
?FC
?Anti-Human?CD25?Alexa?Fluor??488
?53-0259
?BC96
?FC
?Anti-Human?CD25?APC
?17-0259
?BC96
?FC
?Anti-Human?CD25?APC-eFluor??780
?47-0259
?BC96
?FC
?Anti-Human?CD25?Biotin
?13-0259
?BC96
?FC
?Anti-Human?CD25?eFluor??450
?48-0259
?BC96
?FC
?Anti-Human?CD25?PE
?12-0259
?BC96
?FC
?Anti-Human?CD25?PE-Cyanine5
?15-0259
?BC96
?FC
?Anti-Human?CD25?PE-Cyanine7
?25-0259
?BC96
?FC
?Anti-Human?CD25?PerCP-Cyanine5.5
?45-0259
?BC96
?FC
?Anti-Human?CD25?Purified
?14-0259
?BC96
?FC
?Anti-Human/Non-Human?Primate?CD25?APC
?17-0257
?CD25-4E3
?FC
?Anti-Human/Non-Human?Primate?CD25?eFluor??450
?48-0257
?CD25-4E3
?FC
?Anti-Human/Non-Human?Primate?CD25?PE
?12-0257
?CD25-4E3
?FC
?Anti-Human/Non-Human?Primate?CD25?PE-Cyanine7
?25-0257
?CD25-4E3
?FC
?Anti-Human/Non-Human?Primate?CD25?PE-eFluor??610
?61-0257
?CD25-4E3
?FC
?Anti-Human/Non-Human?Primate?CD25?PerCP-eFluor??710
?46-0257
?CD25-4E3
?FC
?Anti-Mouse?CD25?Alexa?Fluor??488
?53-0253
?eBio3C7?(3C7)
?FC
?Anti-Mouse?CD25?eFluor??450
?48-0253
?eBio3C7?(3C7)
?FC
?Anti-Mouse?CD25?Functional?Grade?Purified
?16-0253
?eBio3C7?(3C7)
?FC,?FA
?Anti-Mouse?CD25?Alexa?Fluor??488
?53-0252
?eBio7D4?(7D4)
?FC
?Anti-Mouse?CD25?Biotin
?13-0252
?eBio7D4?(7D4)
?FC
?Anti-Mouse?CD25?eFluor??660
?50-0252
?eBio7D4?(7D4)
?FC
?Anti-Rat?CD25?APC
?17-0390
?OX39
?FC,?IHC
?Anti-Rat?CD25?Biotin
?13-0390
?OX39
?FC,?IHC
?Anti-Rat?CD25?Functional?Grade?Purified
?16-0390
?OX39
?FC,?FA
?Anti-Rat?CD25?PE
?12-0390
?OX39
?FC
?Anti-Rat?CD25?PerCP-eFluor??710
?46-0390
?OX39
?FC
?Anti-Rat?CD25?Purified
?14-0390
?OX39
?FC,?IHC
?Anti-Canine?CD25?eFluor??660
?50-0250
?P4A10
?FC
?Anti-Canine?CD25?FITC
?11-0250
?P4A10
?FC
?Anti-Canine?CD25?PE
?12-0250
?P4A10
?FC
?Anti-Mouse?CD25?Alexa?Fluor??488
?53-0251
?PC61.5
?FC
?Anti-Mouse?CD25?PE-Cyanine5.5
?35-0251
?PC61.5
?FC
?Anti-Mouse?CD25?Alexa?Fluor??700
?56-0251
?PC61.5
?FC
?Anti-Mouse?CD25?APC
?17-0251
?PC61.5
?FC
?Anti-Mouse?CD25?APC-eFluor??780
?47-0251
?PC61.5
?FC
?Anti-Helios?eFluor??450
?48-9883
?22F6?
?FC
?Anti-Mouse?Dectin-1?PE
?12-5859
?bg1fpj?
?FC
?Anti-Mouse?ST2?(IL-33R)?PerCP-eFluor??710
?46-9335
?RMST2-2?
?FC
?Anti-Human?CD294?(CRTH2)?eFluor??660
?50-2949
?BM16
?FC
?Anti-Human?AHR?eFluor??660
?50-9854
?FF3399
?FC
?Human?IL-23?Recombinant?Protein?Carrier-Free
?34-8239

?FA?
?Anti-Human?IL-17AF?eFluor??450
?48-9179
?20LJS09?
?FC

?

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