膿毒癥被定義為由宿主對(duì)感染反應(yīng)失調(diào)引起的危及生命的器官功能障礙。膿毒癥的發(fā)病機(jī)制是十分復(fù)雜的,膿毒癥誘導(dǎo)的全身性促炎階段是器官衰竭和隨后死亡的關(guān)鍵驅(qū)動(dòng)因素之一。嗜粘蛋白-阿克曼氏菌Akkermansia muciniphila (AKK)被認(rèn)為是一種功能性益生菌菌株,對(duì)許多疾病的發(fā)展具有有益作用;然而,AKK是否參與膿毒癥的發(fā)病機(jī)制仍不清楚。最近,南方醫(yī)科大學(xué)研究團(tuán)隊(duì)在期刊《Gut》(IF=24.5)上發(fā)表題為“Novel tripeptide RKH derived from Akkermansia muciniphila protects against lethal sepsis.”的文章,該研究團(tuán)隊(duì)的研究結(jié)果評(píng)估了AKK對(duì)致死性膿毒癥發(fā)展的潛在貢獻(xiàn)。研究顯示活的AKK能夠產(chǎn)生一種新的三肽Arg-Lys-His (RKH),這種肽能在小鼠和豬模型中都能抵抗致命的膿毒癥。RKH直接與托樣受體4結(jié)合,抑制膿毒癥期間的全身炎癥。該研究確定RKH是對(duì)抗膿毒癥引起的全身性炎癥和致死率的一種新的潛在治療方法。
本文中使用了欣博盛Mouse IL-1β和 IL-6 ELISA kits, Porcine IL-1β和 IL-6 ELISA kits?檢測(cè)了血漿中目標(biāo)蛋白的含量。
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1.文章題目:Novel tripeptide RKH derived from Akkermansia muciniphila protects against lethal sepsis.
期 ???刊:Gut(影響因子:24.5)
發(fā)表時(shí)間:7?December?2023
作 ???者:Xie S, Li J, Lyu F, et al.
作者單位:南方醫(yī)科大學(xué)?
使用產(chǎn)品:Mouse IL-1β and IL-6 ELISA kits, Porcine IL-1β and IL-6 ELISA kits
https://pubmed.ncbi.nlm.nih.gov/37553229/
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2.文章題目:Self‐Healing Porous Microneedles Fabricated Via Cryogenic Micromoulding and Phase Separation for Efficient Loading and Sustained Delivery of Diverse Therapeutics.
期 ???刊:Small(影響因子:13.3)
發(fā)表時(shí)間:1?December?2023
作 ???者:Ling Z, Zheng Y, Li Z, et al.
作者單位:中國(guó)科學(xué)院杭州醫(yī)學(xué)研究所?
使用產(chǎn)品:Mouse IFN-γ ELISA kit
https://pubmed.ncbi.nlm.nih.gov/38018331/
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3.文章題目:TS-2021, a third‐generation oncolytic adenovirus that carried Ki67 promoter, TGF-β2 5’?UTR, and IL-15 against experimental glioblastoma.
期 ???刊:Journal of Medical Virology(影響因子:12.7)
發(fā)表時(shí)間:27?December?2023
作 ???者:Wang J, Zhang J, Zhang Q, et al.
作者單位:首都醫(yī)科大學(xué)?
使用產(chǎn)品:Human IL-15 and MMP-3 ELISA kits
https://pubmed.ncbi.nlm.nih.gov/38149454/
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4.文章題目:Microplastics and Nanoplastics Impair the Biophysical Function of Pulmonary Surfactant by Forming Heteroaggregates at the Alveolar–Capillary Interface.
期 ???刊:Environmental Science & Technology(影響因子:11.4)
發(fā)表時(shí)間:6?December?2023
作 ???者:Xu X, Goros R A, Dong Z, et al.
作者單位:中國(guó)科學(xué)院生態(tài)環(huán)境科學(xué)研究中心?
使用產(chǎn)品:Mouse IL-6 ELISA kit
https://pubmed.ncbi.nlm.nih.gov/38055865/
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5.文章題目:Nanointegrative Glycoengineering‐Activated Necroptosis of Triple Negative Breast Cancer Stem Cells Enables Self‐Amplifiable Immunotherapy for Systemic Tumor Rejection.
期 ???刊:?Advanced Healthcare Materials(影響因子:10)
發(fā)表時(shí)間:28?December?2023
作 ???者:Zhao Y, Li Y, He J, et al.
作者單位:貴州醫(yī)科大學(xué)?
使用產(chǎn)品:Mouse TNF-α ELISA kit
https://pubmed.ncbi.nlm.nih.gov/38154036/
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6.文章題目:An injectable gel based on photo-cross-linkable hyaluronic acid and mesoporous bioactive glass nanoparticles for periodontitis treatment.
期 ???刊:International Journal of Biological Macromolecules(影響因子:8.2)??
發(fā)表時(shí)間:12?December?2023
作 ???者:Hu Z, Lv X, Zhang H, et al.
作者單位:華東理工大學(xué)?
使用產(chǎn)品:Mouse IL-6 and TNF-α?ELISA kits
https://pubmed.ncbi.nlm.nih.gov/38052282/
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7.文章題目:Empagliflozin alleviates the development of autoimmune myocarditis via inhibiting NF-κB-dependent cardiomyocyte pyroptosis.
期 ???刊:Biomedicine & Pharmacotherapy(影響因子:7.5)
發(fā)表時(shí)間:1?December?2023
作 ???者:Lv C, Hu C, Zhu C, et al.
作者單位:華中科技大學(xué)?
使用產(chǎn)品:Mouse IL-17, IL-23 and IL-18 ELISA kits
https://pubmed.ncbi.nlm.nih.gov/38042114/
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8.文章題目:Umbilical cord mesenchymal stromal cells in serum-free defined medium display an improved safety profile.
期 ???刊:Stem Cell Research & Therapy(影響因子:7.5)
發(fā)表時(shí)間:12?December?2023
作 ???者:Wu X, Ma Z, Yang Y, et al.
作者單位:西安交通大學(xué)?
使用產(chǎn)品:Rat IFN-γ, TNF-α, IL-4, and IL-6 ELISA kits
https://pubmed.ncbi.nlm.nih.gov/38087382/
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9.文章題目:Bacopaside I alleviates depressive-like behaviors by modulating the gut microbiome and host metabolism in CUMS-induced mice.
期 ???刊:Biomedicine & Pharmacotherapy(影響因子:7.5)
發(fā)表時(shí)間:19?December?2023
作 ???者:Wang J, Xin J, Xu X, et al.
作者單位:海軍軍醫(yī)大學(xué)?
使用產(chǎn)品:Mouse IL-1β, IL-6, and TNF-α ELISA kits
樣本類型:小鼠大腦皮質(zhì)、海馬和結(jié)腸組織
https://pubmed.ncbi.nlm.nih.gov/38113632/
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10.文章題目:C3a/C3aR synergies with TGF-β to promote epithelial-mesenchymal transition of renal tubular epithelial cells via the activation of the NLRP3 inflammasome.
期 ???刊:Journal of Translational Medicine(影響因子:7.4)??
發(fā)表時(shí)間:11?December?2023
作 ???者:You D, Nie K, Wu X, et al.
作者單位:福建醫(yī)科大學(xué)?
使用產(chǎn)品:Mouse IL-1β ELISA kit
https://pubmed.ncbi.nlm.nih.gov/38082306/
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11.文章題目:LFA-1 regulated by IL-2/STAT5 pathway boosts antitumor function of intratumoral CD8+ T cells for improving anti-PD-1 antibody therapy.
期 ???刊:OncoImmunology(影響因子:7.2)??
發(fā)表時(shí)間:14?December?2023
作 ???者:Shan J, Jing W, Ping Y, et al.
作者單位:鄭州大學(xué)?
使用產(chǎn)品:Mouse IFN-γ?and IL-2 ELISA kits?
https://www.tandfonline.com/doi/full/10.1080/2162402X.2023.2293511
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12.文章題目:CaO2-Cu2O micromotors accelerate infected wound healing through antibacteria, hemostasis, improved cell migration, and inflammatory regulation.
期 ???刊:Journal of Materials Chemistry B(影響因子:7)
發(fā)表時(shí)間:1?December?2023
作 ???者:Liu G, Zu M, Wang L, et al.
作者單位:西南大學(xué)?
使用產(chǎn)品:Goat anti-rabbit IgG (H + L)
https://pubmed.ncbi.nlm.nih.gov/38086697/
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13.文章題目:Sporopollenin exine capsules modulate the function of microglial cells.?
期 ???刊:Biomaterials Science(影響因子:6.6)??
發(fā)表時(shí)間:5?December?2023
作 ???者:Li M, Hu B, Wu Z, et al.
作者單位:廈門(mén)大學(xué)?
使用產(chǎn)品:Mouse TNF-α and IL-1β ELISA kits
https://pubmed.ncbi.nlm.nih.gov/38099812/
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14.文章題目:Effects of unfolding treatment assisted glycation on the IgE/IgG binding capacity and antioxidant activity of ovomucoid.
期 ???刊:Food & Function(影響因子:6.1)
發(fā)表時(shí)間:6?December?2023
作 ???者:Xia X, Li J, Liang R, et al.
作者單位:遵義醫(yī)學(xué)院?
使用產(chǎn)品:HRP-streptavidin
https://pubmed.ncbi.nlm.nih.gov/38047408/
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15.文章題目:The Potential Role of Moringa oleifera Lam. Leaf Proteins in Moringa Allergy by Functionally Activating Murine Bone Marrow-Derived Dendritic Cells and Inducing Their Differentiation toward a Th2-Polarizing Phenotype.
期 ???刊:Nutrients(影響因子:5.9)
發(fā)表時(shí)間:19?December?2023
作 ???者:Xi C, Li W, Liu X, et al.
作者單位:云南農(nóng)業(yè)大學(xué)
使用產(chǎn)品:Mouse TNF-α and IL-12p70 ELISA kits
https://www.mdpi.com/2072-6643/16/1/7
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16.文章題目:FGF21 alleviates endothelial mitochondrial damage and prevents BBB from disruption after intracranial hemorrhage through a mechanism involving SIRT6.
期 ???刊:Molecular Medicine(影響因子:5.7)
發(fā)表時(shí)間:4?December?2023
作 ???者:Wang R, Wang J, Zhang Z, et al.
作者單位:空軍軍醫(yī)大學(xué)?
使用產(chǎn)品:Human FGF-21 ELISA kit
https://pubmed.ncbi.nlm.nih.gov/38049769/
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17.文章題目:BAFF deficiency aggravated optic nerve crush-induced retinal ganglion cells damage by regulating apoptosis and neuroinflammation via NF-κB-IκBα signaling.?
期 ???刊:International Immunopharmacology(影響因子:5.6)?
發(fā)表時(shí)間:4?December?2023
作 ???者:Lin J, Deng W, Liao J, et al. ?
作者單位:廣西壯族自治區(qū)人民醫(yī)院
使用產(chǎn)品:Mouse TNF-α, IL-1β and IFN-γ ELISA kits?
https://pubmed.ncbi.nlm.nih.gov/38041956/
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18.文章題目:Menstrual blood-derived stem cells exosomal miR-let-7 to ameliorate pulmonary fibrosis through inhibiting ferroptosis by Sp3/HDAC2/Nrf2 signaling pathway.
期 ???刊:International Immunopharmacology(影響因子:5.6)
發(fā)表時(shí)間:5?December?2023
作 ???者:Sun L, He X, Kong J, et al.
作者單位:浙江省中西醫(yī)結(jié)合醫(yī)院?
使用產(chǎn)品:Mouse IL-6 and IL-1β ELISA kits
https://pubmed.ncbi.nlm.nih.gov/38056200/
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19.文章題目:Discovery of a novel pyroptosis inhibitor acting though modulating glutathionylation to suppress NLRP3-related signal pathway.
期 ???刊:International Immunopharmacology(影響因子:5.6)??
發(fā)表時(shí)間:10?December?2023
作 ???者:Zhou N, Zhang Y, Jiao Y, et al.
作者單位:四川大學(xué)華西藥學(xué)院
使用產(chǎn)品:Mouse IL-1β ELISA kit
https://pubmed.ncbi.nlm.nih.gov/38082306/
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20.文章題目:Multiple bioactivities of choerospondin obtained from blossom of Citrus aurantium L. Var. Amara engl. And its anti-inflammation and anti-atherosclerosis action pathways.
期 ???刊:Journal of Functional Foods(影響因子:5.6)
發(fā)表時(shí)間:11?December?2023
作 ???者:Hao K X, Shen C Y, Zhong R F, et al.
作者單位:華南理工大學(xué)?
使用產(chǎn)品:Mouse IL-6, TNF-α and IL-1β ELISA kits
https://www.sciencedirect.com/science/article/pii/S1756464623005418
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21.文章題目:EZY-1 inhibits idiopathic pulmonary fibrosis by regulating M2-type macrophage differentiation.
期 ???刊:Journal of Functional Foods(影響因子:5.6)
發(fā)表時(shí)間:14?December?2023
作 ???者:Wu J, Tu M, Wei T, et al.
作者單位:廣東醫(yī)科大學(xué)?
使用產(chǎn)品:Mouse TGF-β1 ELISA kit
https://www.sciencedirect.com/science/article/pii/S1756464623005480
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22.文章題目:Panax notoginseng saponin R1 improves glucocorticoid-inhibited airway epithelium repair via glucocorticoid receptor β.
期 ???刊:International Immunopharmacology(影響因子:5.6)
發(fā)表時(shí)間:16?December?2023
作 ???者:Yang L, Xu M, Zhang L, et al.
作者單位:重慶醫(yī)科大學(xué)附屬兒童醫(yī)院
使用產(chǎn)品:Mouse IL-33 and TSLP ELISA kits
樣本類型:肺泡灌洗液
https://pubmed.ncbi.nlm.nih.gov/38104367/
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23.文章題目:HIF-1α promotes virus replication and cytokine storm in H1N1 virus-induced severe pneumonia through cellular metabolic reprogramming.
期 ???刊:Virologica Sinica(影響因子:5.5)
發(fā)表時(shí)間:1?December?2023
作 ???者:Meng X, Zhu Y, Yang W, et al.
作者單位:上海交通大學(xué)?
使用產(chǎn)品:Mouse IFN-α and IFN-β ELISA kits
樣本類型:肺泡灌洗液
https://pubmed.ncbi.nlm.nih.gov/38042371/
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24.文章題目:Sedative and hypnotic effects of Polygala tenuifolia willd. saponins on insomnia mice and their targets.
期 ???刊:Journal of Ethnopharmacology(影響因子:5.4)
發(fā)表時(shí)間:22?December?2023
作 ???者:Hao K X, Shen C Y, Jiang J G.
作者單位:華南理工大學(xué)?
使用產(chǎn)品:Mouse IL-1β and TNF-α ELISA kits
https://pubmed.ncbi.nlm.nih.gov/38056805/
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25.文章題目:Abelmoschus manihot (L.) medik. seeds alleviate rheumatoid arthritis by modulating JAK2/STAT3 signaling pathway.
期 ???刊:Journal of Ethnopharmacology(影響因子:5.4)
發(fā)表時(shí)間:25?December?2023
作 ???者:Tao Y, Liu J, Li M, et al.
作者單位:成都中醫(yī)藥大學(xué)?
使用產(chǎn)品:Rat TNF-α and IL-1β ELISA kits
https://pubmed.ncbi.nlm.nih.gov/38151179/
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26.文章題目:Advanced Glycation End Products-Induced Activation of Keratinocytes: A Mechanism Underlying Cutaneous Immune Response in Psoriasis.?
期 ???刊:Journal of Innate Immunity(影響因子:5.3)??
發(fā)表時(shí)間:1?December?2023
作 ???者:Kang P, Chen J, Wang S, et al.
作者單位:第四軍醫(yī)大學(xué)西京醫(yī)院?
使用產(chǎn)品:Human IL-36α, IL-36β and IL-36γ ELISA kits
https://pubmed.ncbi.nlm.nih.gov/37989127/
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27.文章題目:BACH1 Loss Exerts Antitumor Effects on Mantle Cell Lymphoma Cells via Inducing a Tumor-Intrinsic Innate Immune Response and Cell-Cycle Arrest.
期 ???刊:Molecular Cancer Research(影響因子:5.2)
發(fā)表時(shí)間:1?December?2023
作 ???者:Li G, Feng M, Zhang Z, et al.
作者單位:中國(guó)醫(yī)學(xué)科學(xué)院?
使用產(chǎn)品:Human IFN-α?and IFN-β ELISA kits
https://pubmed.ncbi.nlm.nih.gov/37713314/
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28.文章題目:Bisdemethoxycurcumin, a curcumin derivative, ameliorates adjuvant-induced arthritis by suppressing inflammatory reactions and macrophage migration.
期 ???刊:Chemico-Biological Interactions(影響因子:5.1)
發(fā)表時(shí)間:5?December?2023
作 ???者:Sun X, Liang Y, Wang Y, et al.
作者單位:煙臺(tái)毓璜頂醫(yī)院?
使用產(chǎn)品:Rat TNFα, IL-6, and IL-1β ELISA kits
https://pubmed.ncbi.nlm.nih.gov/38056805/
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29.文章題目:?Fusobacterium nucleatum exacerbates the progression of pulpitis by regulating the STING‐dependent pathway.
期 ???刊:The FASEB Journal(影響因子:4.8)
發(fā)表時(shí)間:12?December?2023
作 ???者:Zhou L, Mao H Q, Li J Q, et al.
作者單位:武漢大學(xué)口腔醫(yī)學(xué)院?
使用產(chǎn)品:Mouse IFN-β ELISA kit
https://pubmed.ncbi.nlm.nih.gov/38085169/
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30.文章題目:Infliximab alleviates memory impairment in rats with chronic pain by suppressing neuroinflammation and restoring hippocampal neurogenesis.
期 ???刊:Neuropharmacology(影響因子:4.7)
發(fā)表時(shí)間:16?December?2023
作 ???者:Yao R, Man Y, Lu Y, et al.
作者單位:徐州市第一人民醫(yī)院
使用產(chǎn)品:Rat TNF-α and IL-1β ELISA kits
樣本類型:海馬組織
https://pubmed.ncbi.nlm.nih.gov/38110173/
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31.文章題目:Amelioration of Atherosclerosis by lycopene is linked to the modulation of gut microbiota dysbiosis and related gut-heart axis activation in high-fat diet-fed ApoE?/? mice.
期 ???刊:Nutrition & Metabolism(影響因子:4.5)
發(fā)表時(shí)間:1?December?2023
作 ???者:Tu T, Liu H, Liu Z, et al.
作者單位:南方醫(yī)科大學(xué)?
使用產(chǎn)品:Mouse MCP-1, TNF-α,?IL-1βand IL-6?ELISA kits
https://pubmed.ncbi.nlm.nih.gov/38041095/
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32.文章題目:Mastoparan M Suppressed NLRP3 Inflammasome Activation by Inhibiting MAPK/NF-κB and Oxidative Stress in Gouty Arthritis.
期 ???刊:Journal of Inflammation Research(影響因子:4.5)
發(fā)表時(shí)間:15?December?2023
作 ???者:Yan Y, Yu L, Chen B, et al.
作者單位:廈門(mén)大學(xué)
使用產(chǎn)品:Mouse IL-1β ELISA kit?
樣本類型:小鼠后爪組織
https://www.tandfonline.com/doi/full/10.2147/JIR.S434587
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33.文章題目:NeuroD1-GPX4 signaling leads to ferroptosis resistance in hepatocellular carcinoma.
期 ???刊:PLoS genetics(影響因子:4.5)
發(fā)表時(shí)間:22?December?2023
作 ???者:Huang P, Duan W, Ruan C, et al.
作者單位:重慶大學(xué)?
使用產(chǎn)品:Annexin V-FITC/PI apoptosis assay kit
https://pubmed.ncbi.nlm.nih.gov/38134213/
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34.文章題目:Evaluation of the immunoprotective effects of porcine deltacoronavirus subunit vaccines.
期 ???刊:Virology(影響因子:3.7)
發(fā)表時(shí)間:2?December?2023
作 ???者:Yu R, Zhang L, Zhou P, et al.
作者單位:中國(guó)農(nóng)業(yè)科學(xué)院蘭州獸醫(yī)研究所?
使用產(chǎn)品:Mouse and Porcine IFN-γ and IL-4 ELISA kits
https://pubmed.ncbi.nlm.nih.gov/38070302/
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35.文章題目:A comparative study of platelet storage lesion in platelet-rich plasma under cryopreservation.
期 ???刊:Annals of Hematology(影響因子:3.5)
發(fā)表時(shí)間:18?December?2023
作 ???者:Dang E, Chen Y, Wang W, et al.
作者單位:第四軍醫(yī)大學(xué)西京醫(yī)院?
使用產(chǎn)品:Human IL-1β ELISA Kit
https://pubmed.ncbi.nlm.nih.gov/38110587/
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36.文章題目:Integrated metabolomics and network pharmacology revealed the key active ingredients for the treatment of ulcerative colitis in the Citrus reticulata ‘Dahongpao’peel.
期 ???刊:Journal of Pharmaceutical and Biomedical Analysis(影響因子:3.4)
發(fā)表時(shí)間:1?December?2023
作 ???者:Li X, Wang Q, Wang M, et al.
作者單位:成都中醫(yī)藥大學(xué)?
使用產(chǎn)品:Mouse TNF-α ELISA kit
https://pubmed.ncbi.nlm.nih.gov/38056284/
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37.文章題目:Electroacupuncture ameliorates AOM/DSS-induced mice colorectal cancer by inhibiting inflammation and promoting autophagy via the SIRT1/miR-215/Atg14 axis.
期 ???刊:Aging(影響因子:3.4)
發(fā)表時(shí)間:1 December?2023
作 ???者:Li J, Han Y, Zhou M, et al.
作者單位:華中科技大學(xué)同濟(jì)醫(yī)學(xué)院
使用產(chǎn)品:Mouse IL-6, IL-17, IL-10 and TNF-α ELISA kits
樣本類型:結(jié)腸組織
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10713401/
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38.文章題目:Fluoxetine mitigates depressive-like behaviors in mice via anti-inflammation and enhancing neuroplasticity.
期 ???刊:Brain Research(影響因子:2.9)
發(fā)表時(shí)間:13?December?2023
作 ???者:Qian X, Zhong Z, Zhang Y, et al.
作者單位:中山大學(xué)?
使用產(chǎn)品:Mouse TNF-α and IL-6 ELISA kits
https://pubmed.ncbi.nlm.nih.gov/38101693/
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39.文章題目:Dapansutrile Ameliorates Atrial Inflammation and Vulnerability to Atrial Fibrillation in HFpEF Rats.
期 ???刊:Heart, Lung and Circulation(影響因子:2.6)
發(fā)表時(shí)間:1?December?2023
作 ???者:Yang H, Zhu J, Fu H, et al. ?
作者單位:武漢大學(xué)人民醫(yī)院?
使用產(chǎn)品:Rat IL-1β, IL-6, and TNF-α ELISA kits
https://pubmed.ncbi.nlm.nih.gov/38040503/
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40.文章題目:Reduction of acute radiation-induced brain injury in rats by anlotinib.
期 ???刊:Neuroreport(影響因子:1.7)
發(fā)表時(shí)間:1?December?2023
作 ???者:Xiong Y, Zhou X, Yu C, et al.
作者單位:南京醫(yī)科大學(xué)淮安第一人民醫(yī)院?
使用產(chǎn)品:Rat IL-6 ELISA kit
https://pubmed.ncbi.nlm.nih.gov/38109375/
41.文章題目:Generation of a human embryonic stem cell line (SMUDHe010-A-1B) carrying inducible DTA expression cassette in the AAVS1 locus by CRISPR/Cas9-mediated homologous recombination.
期 ???刊:Stem Cell Research(影響因子:1.2)
發(fā)表時(shí)間:15?December?2023
作 ???者:Qiu B, Zheng W, Zhong Y, et al.
作者單位:南方醫(yī)科大學(xué)?
使用產(chǎn)品:BSA
https://pubmed.ncbi.nlm.nih.gov/38103335/
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