近期,青海省人民醫(yī)院趙強(qiáng)強(qiáng)團(tuán)隊(duì)在Molecular Cancer(IF=27.7)上發(fā)表題為“Unveiling the PDK4-centered rituximab-resistant mechanism in DLBCL: the potential of the “Smart”?exosome nanoparticle therapy.”的研究。彌漫性大B細(xì)胞淋巴瘤(DLBCL)中利妥昔單抗(rituximab)耐藥的關(guān)鍵機(jī)制主要涉及PDK4對CD20表達(dá)的負(fù)調(diào)控。研究團(tuán)隊(duì)發(fā)現(xiàn),PDK4通過磷酸化HDAC8調(diào)節(jié)CD20表達(dá),導(dǎo)致利妥昔單抗耐藥。為此,團(tuán)隊(duì)開發(fā)了一種外泌體納米顆粒復(fù)合物,通過靶向PDK4/HDAC8/CD20途徑有效克服耐藥性,為DLBCL患者的治療提供了新的策略。
該項(xiàng)研究中,使用了欣博盛生物(NeoBioscience Technology Co, Ltd)的Mouse?TNF-α, IFN-γ, IL-12和IL-6 ELISA Kits,用于檢測樣本中相關(guān)指標(biāo)的含量。
貨號 | 產(chǎn)品名稱 | 靈敏度 | 檢測范圍 |
EMC102a? ? ? ? ? ?? | QuantiCyto? Mouse TNF-α ELISA kit(小鼠腫瘤壞死因子-α) | 15.6pg/ml? ? ? ? ? ? | 31.25-2000pg/ml? ? ? ? ? ?? |
EMC101g | QuantiCyto? Mouse IFN-γ ELISA kit(小鼠γ干擾素) | 3.9pg/ml | 7.8-500pg/ml |
EMC006 | QuantiCyto? Mouse IL-12p70 ELISA kit(小鼠白細(xì)胞介素-12p70)? ? ? ? ? ? | 7.8pg/ml | 15.6-1000pg/ml |
EMC004 | QuantiCyto? Mouse IL-6 ELISA kit(小鼠白細(xì)胞介素-6) | 7.8pg/ml | 15.6-1000pg/ml |
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欣博盛生物非常榮幸能夠作為供應(yīng)商為該項(xiàng)研究提供高品質(zhì)ELISA試劑盒,為生物醫(yī)學(xué)領(lǐng)域的科研探索貢獻(xiàn)一份力量。
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2024年7月文獻(xiàn)引用
1.?Unveiling the PDK4-centered rituximab-resistant mechanism in DLBCL: the potential of the "Smart" exosome nanoparticle therapy.(Molecular Cancer, IF=27.7)
發(fā)表時間:2024/7/15
作者:Wu X, Ban C, Deng W, et al.
作者單位:中南大學(xué)湘雅三醫(yī)院
使用產(chǎn)品:Human TNF-α, IFN-γ, IL-12, and IL-6 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/39004737/
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2.?Cartilage lacuna-biomimetic hydrogel microspheres endowed with integrated biological signal boost endogenous articular cartilage regeneration.(Bioactive Materials, IF=18)
發(fā)表時間:2024/7/12
作者:Li H, Zhao T, Yuan Z, et al.
作者單位:南開大學(xué)
使用產(chǎn)品:Rat PDGF-BB ELISA Kit
https://www.sciencedirect.com/science/article/pii/S2452199X24002603
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3.?C-JUN overexpressing CAR-T cells in acute myeloid leukemia: preclinical characterization and phase I trial.(Nature Communications, IF=14.7)
發(fā)表時間:2024/7/22
作者:Zuo S, Li C, Sun X, et al.
作者單位:中國醫(yī)學(xué)科學(xué)院血液病醫(yī)院
使用產(chǎn)品:Human IL-15 ELISA Kit
https://pubmed.ncbi.nlm.nih.gov/39039086/
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4.?Orchestrating NK and T cells via tri-specific nano-antibodies for synergistic antitumor immunity.(Nature Communications, IF=14.7)
發(fā)表時間:2024/7/23
作者:Ye Q N, Zhu L, Liang J, et al.
作者單位:華南理工大學(xué)
使用產(chǎn)品:Human IFN-γ, Perforin and Granzyme B ELISA Kits
樣本類型:腫瘤組織
https://pubmed.ncbi.nlm.nih.gov/39043643/
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5.?rs-TAC PDC, a peptide drug-conjugate, for targeted delivery of tacrolimus and sericin alleviates podocyte injury in diabetic nephropathy.(Nano Today, IF=13.2)
發(fā)表時間:2024/7/8
作者:Gao S, Li Y, Zhu T, et al.
作者單位:南京大學(xué)醫(yī)學(xué)院附屬金陵醫(yī)院
使用產(chǎn)品:Mouse albumin, TNF-α and IL-6 ELISA Kit
樣本類型:尿液樣本
https://www.sciencedirect.com/science/article/abs/pii/S174801322400241X
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6.?A Janus Microsphere Delivery System Orchestrates Immunomodulation and Osteoinduction by Fine-tuning Release Profiles.(Small, IF=13)
發(fā)表時間:2024/7/10
作者:Shi Y, Gu J, Zhang C, et al.
作者單位:浙江大學(xué)醫(yī)學(xué)院附屬口腔醫(yī)院
使用產(chǎn)品:Human BMP-2 ELISA Kit
樣本類型:其他樣本
https://pubmed.ncbi.nlm.nih.gov/38984921/
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7.?Bacteroides fragilis alleviates necrotizing enterocolitis through restoring bile acid metabolism balance using bile salt hydrolase and inhibiting FXR-NLRP3 signaling pathway.(Gut Microbes, IF=12.2)
發(fā)表時間:2024/7/16
作者:Chen Z, Chen H, Huang W, et al.
作者單位:南方醫(yī)科大學(xué)
使用產(chǎn)品:Rat IL-1β ELISA Kit
樣本類型:回腸組織
https://pubmed.ncbi.nlm.nih.gov/39013030/
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8.?A fructan-type garlic polysaccharide upregulates immune responses in macrophage cells and in immunosuppressive mice.(Carbohydrate Polymers, IF=10.7)
發(fā)表時間:2024/7/25
作者:Wu J, Yu G, Zhang X, et al.
作者單位:暨南大學(xué)
使用產(chǎn)品:Mouse IL-6, TNF-α, IFN-γ, IgA and IgG ELISA Kits
https://www.sciencedirect.com/science/article/abs/pii/S0144861724007562
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9.?Graphene oxide quantum dots-loaded sinomenine hydrochloride nanocomplexes for effective treatment of rheumatoid arthritis via inducing macrophage repolarization and arresting abnormal proliferation of fibroblast-like synoviocytes.(Journal of Nanobiotechnology, IF=10.6)
發(fā)表時間:2024/7/1
作者:Lin Y, Tang Y, Yi O, et al.
作者單位:湖南中醫(yī)藥大學(xué)第一醫(yī)院
使用產(chǎn)品:Mouse TNF-α, IL-6 and IL-10 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/38951875/
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10.?Separable nanocomposite hydrogel microneedles for intradermal and sustained delivery of antigens to enhance adaptive immune responses.(Acta Biomaterialia, IF=9.4)
發(fā)表時間:2024/7/23
作者:Zheng Y, Li Z, Li S, et al.
作者單位:中國科學(xué)院杭州醫(yī)學(xué)研究所
使用產(chǎn)品:Mouse INF-γ, TNF-α and IL-6 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/39053817/
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11.?Anti-inflammation mechanisms of a homogeneous polysaccharide from Phyllanthus emblica L. on DSS induced colitis mice via the gut microbiota and metabolites alteration.(Food Chemistry, IF=8.5)
發(fā)表時間:2024/7/4
作者:Li X, Chen Y, Peng X, et al.
作者單位:華南農(nóng)業(yè)大學(xué)
使用產(chǎn)品:Mouse TNF-α, IL-6 and IL-10 ELISA Kits
樣本類型:結(jié)腸組織
https://pubmed.ncbi.nlm.nih.gov/38981378/
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12.?Physicochemical evaluation, structural characterization, in vitro and in vivo bioactivities of water-soluble polysaccharides from Luobuma (Apocynum L.) tea.(Food Chemistry, IF=8.5)
發(fā)表時間:2024/7/26
作者:Abubakar A S, Ahmad B, Ahmad N, et al.
作者單位:中國農(nóng)業(yè)科學(xué)院
使用產(chǎn)品:Mouse IL-6 ELISA Kit
https://pubmed.ncbi.nlm.nih.gov/39067428/
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13.?Allergenicity assessment of β-lactoglobulin ferulic acid–glucose conjugates.(Food Chemistry, IF=8.5)
發(fā)表時間:2024/7/24
作者:Wang Y, Zhang K, Chen W, et al.
作者單位:江西師范大學(xué)
使用產(chǎn)品:Rat TNF-α and IL-4 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/39068806/
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14.?Zinc finger BED-type containing 3 promotes hepatic steatosis by interacting with polypyrimidine tract-binding protein 1.(Diabetologia, IF=8.4)
發(fā)表時間:2024/7/22
作者:Wu Y, Yang M, Wu S, et al.
作者單位:重慶大學(xué)附屬三峽醫(yī)院
使用產(chǎn)品:Histostain-Plus IHC Kit
https://pubmed.ncbi.nlm.nih.gov/39037604/
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15.?DNA Origami Enhanced Cytokine Immunotherapy for Alleviating Renal Ischemia-Reperfusion Injury.(ACS Applied Materials & Interfaces, IF=8.3)
發(fā)表時間:2024/7/19
作者:Fan Y, Wang C, Dai W, et al.
作者單位:四川大學(xué)華西醫(yī)院
使用產(chǎn)品:Mouse IL-6, IL-1β and TNF-α ELISA Kits
樣本類型:腎組織
https://pubmed.ncbi.nlm.nih.gov/39029244/
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16.?Targeting TANK-binding kinase 1 attenuates painful diabetic neuropathy via inhibiting microglia pyroptosis.(Cell Communication and Signaling, IF=8.2)
發(fā)表時間:2024/7/19
作者:Liao Q, Yang Y, Li Y, et al.
作者單位:南方醫(yī)科大學(xué)第三附屬醫(yī)院
使用產(chǎn)品:Mouse IFN-β and TNF-α ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/39030571/
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17.?Interleukin-11 drives fibroblast metabolic reprogramming in crystalline silica-induced lung fibrosis.(Science of The Total Environment, IF=8.2)
發(fā)表時間:2024/7/22
作者:Xie Y, Yang S, Xu Y, et al.
作者單位:華中科技大學(xué)
使用產(chǎn)品:Mouse TGF-β1 ELISA Kit
樣本類型:支氣管灌洗液
https://pubmed.ncbi.nlm.nih.gov/39047838/
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18.?Chitosan-alginate/R8 ternary polyelectrolyte complex as an oral protein-based vaccine candidate induce effective mucosal immune responses.(International Journal of Biological Macromolecules, IF=7.7)
發(fā)表時間:2024/7/5
作者:Liu Y, Long M, Wang Y, et al.
作者單位:中國農(nóng)業(yè)大學(xué)
使用產(chǎn)品:Mouse IL-17, TNF-α and IgA ELISA Kits
樣本類型:腸道灌洗液
https://pubmed.ncbi.nlm.nih.gov/38971274/
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19.?LncRNA MAAMT facilitates macrophage recruitment and proinflammatory activation and exacerbates autoimmune myocarditis through the SRSF1/NF-κB axis.(International Journal of Biological Macromolecules, IF=7.7)
發(fā)表時間:2024/7/26
作者:Gan T, Liu W, Wang Y, et al.
作者單位:華中科技大學(xué)
使用產(chǎn)品:Mouse IL-1β, IL-6 and TNF-α ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/39069042/
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20.?E3 ubiquitin ligase RNF180 mediates the ALKBH5/SMARCA5 axis to promote colon inflammation and Th17/Treg imbalance in ulcerative colitis mice.(Archives of Pharmacal Research, IF=6.9)
發(fā)表時間:2024/7/27
作者:Wang K, Liu F, Muchu B, et al.
作者單位:中南大學(xué)湘雅醫(yī)院
使用產(chǎn)品:Mouse IL-17A, IFN-γ, IL-6, TNF-α, TGF-β and IL-10 ELISA Kits
樣本類型:組織樣本
https://pubmed.ncbi.nlm.nih.gov/39060657/
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21.?Fe3O4 Nanoparticles That Modulate the Polarisation of Tumor-Associated Macrophages Synergize with Photothermal Therapy and Immunotherapy (PD-1/PD-L1 Inhibitors) to Enhance Anti-Tumor Therapy.(International Journal of Nanomedicine, IF=6.6)
發(fā)表時間:2024/7/17
作者:Sun H, Wang X, Guo Z, et al.
作者單位:上海交通大學(xué)醫(yī)學(xué)院
使用產(chǎn)品:Mouse TNF-α ELISA Kit
https://pubmed.ncbi.nlm.nih.gov/39050876/
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22.?Cell-Cultured Fish Meat via Scale-Up Expansion of Carassius auratus Skeletal Muscle Cells Using Edible Porous Microcarriers and Quality Evaluation.(Journal of Agricultural and Food Chemistry, IF=5.7)
發(fā)表時間:2024/7/10
作者:Yin H, Wang L, Hur S J, et al.
作者單位:中國海洋大學(xué)
使用產(chǎn)品:Human Insulin ELISA Kit
樣本類型:其他樣本
https://pubmed.ncbi.nlm.nih.gov/38987705/
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23.?Matrix-assisted laser desorption ionization mass spectrometry imaging reveals the spatial distribution of compounds that may exacerbate inflammation in garden ginseng and ginseng under forest.(Talanta, IF=5.6)
發(fā)表時間:2024/7/20
作者:Zhao Y M, Li Y N, Ma R, et al.
作者單位:長春中醫(yī)藥大學(xué)
使用產(chǎn)品:Human TNF-α, IL-1β, IL-6, IL-10 and VEGF ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/39053359/
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24.?Trichinella spiralis Infection Inhibits the Efficacy of RBD Protein of SARS-CoV-2 Vaccination via Regulating Humoral and Cellular Immunity.(Vaccines, IF=5.2)
發(fā)表時間:2024/6/30
作者:Zhu F, Zheng W, Gong Y, et al.
作者單位:華中科技大學(xué)
使用產(chǎn)品:Mouse IFN-γ ELISA Kit
樣本類型:支氣管灌洗液
https://pubmed.ncbi.nlm.nih.gov/39066367/
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25.?Influenza Vaccination Mediates SARS-CoV-2 Spike Protein Peptide-Induced Inflammatory Response via Modification of Histone Acetylation.(Vaccines, IF=5.2)
發(fā)表時間:2024/7/1
作者:Zuo Z, Mu Y, Qi F, et al.
作者單位:中山大學(xué)附屬第三醫(yī)院
使用產(chǎn)品:Mouse IL-1β, TNF-α and IFN-γ ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/39066369/
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26.?Neutrophil migration participates in the side effect of recombinant human tissue plasminogen activator.(CNS Neuroscience & Therapeutics, IF=4.8)
發(fā)表時間:2024/7/2
作者:Huang Y, Han Z, Shen T, et al.
作者單位:首都醫(yī)科大學(xué)宣武醫(yī)院
使用產(chǎn)品:Human VCAM-1 ELISA Kit
https://pubmed.ncbi.nlm.nih.gov/38954749/
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27.?Evaluation of the suitability of β-lactoglobulin and whey protein in a BALB/c mouse model of cow's milk allergy.(Food Bioscience, IF=4.8)
發(fā)表時間:2024/7/20
作者:Shao H, Huang M, Bai T, et al.
作者單位:南昌大學(xué)
使用產(chǎn)品:TMB (standard sensitivity)
https://www.sciencedirect.com/science/article/abs/pii/S2212429224012136
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28.?Circadian clock disruption stimulates bone loss via regulatory T cell-Mediated regulation of IL-10 expression.(International Immunopharmacology, IF=4.8)
發(fā)表時間:2024/7/19
作者:Zhu Z, Chen G, Yu S, et al.
作者單位:華中科技大學(xué)
使用產(chǎn)品:Mouse IL-10 and TGF-β1 ELISA Kits
樣本類型:骨髓
https://pubmed.ncbi.nlm.nih.gov/39032468/
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29.?The effect of ethanol extracts of loulu flower on LPS-induced acute lung injury in mice.(Journal of Ethnopharmacology, IF=4.8)
發(fā)表時間:2024/7/6
作者:Han S, Mei S, Lai M, et al.
作者單位:江西中醫(yī)藥大學(xué)
使用產(chǎn)品:Mouse TNF-α and IL-4 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/38972530/
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30.?Benzyl Isothiocyanate and Resveratrol Synergistically Alleviate Dextran Sulfate Sodium-Induced Colitis in Mice.(Foods, IF=4.7)
發(fā)表時間:2024/7/1
作者:Liu J, Zhang Q, Hao H, et al.
作者單位:大連工業(yè)大學(xué)
使用產(chǎn)品:Mouse IL-6, IL-1β, TNF-α and IL-10 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/38998586/
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31.?The prognostic value and its relationship with immune infiltration of ACLY in clear cell renal cell carcinoma.(Translational Oncology, IF=4.5)
發(fā)表時間:2024/7/5
作者:Yin B, Liu Q, Zheng Y, et al.
作者單位:山東第一醫(yī)科大學(xué)第一附屬醫(yī)院
使用產(chǎn)品:Annexin V-FITC/PI apoptosis assay kit
https://pubmed.ncbi.nlm.nih.gov/38970915/
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32.?Specific humoral immune response and XBB variants re-infection risk of hemodialysis patients after Omicron BA.5 infection in China.(Vaccine, IF=4.5)
發(fā)表時間:2024/7/23
作者:Mai W, Shen J, Ma F, et al.
作者單位:廣州醫(yī)科大學(xué)附屬第二醫(yī)院
使用產(chǎn)品:TMB (standard sensitivity)
https://pubmed.ncbi.nlm.nih.gov/39048466/
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33.?Effect of different delivery modes on intestinal microbiota and immune function of neonates.(Scientific reports, IF=3.8)
發(fā)表時間:2024/7/29
作者:Lai C, Huang L, Wang Y, et al.
作者單位:廣西醫(yī)科大學(xué)第三附屬醫(yī)院
使用產(chǎn)品:Human IFN-γ, IL-4 and IL-12p70 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/39075163/
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34.?Surface Proteins of Bifidobacterium Bifidum DNG6 Growing in 2′-FL Alleviating LPS-Induced Intestinal Barrier Injury in vitro.(Journal of Dairy Science, IF=3.7)
發(fā)表時間:2024/7/4
作者:Zhao J, Zhang G, Yang J, et al.
作者單位:東北農(nóng)業(yè)大學(xué)
使用產(chǎn)品:Human TNF-α, IL-6, IL-1β and IL-10 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/38969003/
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35.?Role of Th2, Th17 and Treg Cells and relevant cytokines in pathogenesis of allergic rhinitis.(Allergy, Asthma & Clinical Immunology, IF=2.6)
發(fā)表時間:2024/7/20
作者:Guo L P, Yan M, Niu R B, et al.
作者單位:鄂爾多斯市中心醫(yī)院
使用產(chǎn)品:Human IL-4, IL-5, IL-10 and IL-17 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/39033277/
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36.?Mechanism of Vaginal Epithelial Cell Pyroptosis Induced by the NLRP3 Inflammasome in Vulvovaginal Candidiasis.(American Journal of Reproductive Immunology, IF=2.5)
發(fā)表時間:2024/7/3
作者:Peng Y, Xu Y, Li S, et al.
作者單位:昆明醫(yī)科大學(xué)第一附屬醫(yī)院
使用產(chǎn)品:Mouse IL-1β and IL-18 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/38958245/
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37.?A nanoparticle vaccine based on the VP121–26 and VP2 structural proteins of Senecavirus A induces robust protective immune responses.(Veterinary Microbiology, IF=2.4)
發(fā)表時間:2024/7/25
作者:Cao N, Li Y, Zhang H, et al.
作者單位:華中農(nóng)業(yè)大學(xué)
使用產(chǎn)品:Mouse IL-2, IL-4, IL-10 and IFN-γ ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/39067145/
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38.?The role of CD83 in the pathogenesis of immune thrombocytopenia.(Hematology, IF=2)
發(fā)表時間:2024/7/12
作者:Wang X, Zhou Q, Yang W, et al.
作者單位:昆明醫(yī)科大學(xué)第二附屬醫(yī)院
使用產(chǎn)品:Human IFN-γ, IL-17 and TGF-β1 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/38994874/
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39.?Linoleic Acid Alleviates Lipopolysaccharide Induced Acute Liver Injury via Activation of Nrf2.(Physiological research, IF=1.9)
發(fā)表時間:2024/7/13
作者:ZHANG Q, JIANG Y, QIN Y, et al.
作者單位:重慶醫(yī)科大學(xué)附屬大學(xué)城醫(yī)院
使用產(chǎn)品:Mouse TNF-α and IL-6 ELISA Kits
樣本類型:肝組織
https://pubmed.ncbi.nlm.nih.gov/39027955/
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40.?Basic Fibroblast Growth Factor Accumulation in Culture Medium Masks the Direct Antitumor Effect of Anti-VEGF Agent Bevacizumab.(Doklady Biochemistry and Biophysics, IF=0.8)
發(fā)表時間:2024/7/13
作者:Wang Z, Wang Z, Deng L, et al.
作者單位:遵義醫(yī)科大學(xué)珠海校區(qū)
使用產(chǎn)品:Human bFGF ELISA Kit
https://pubmed.ncbi.nlm.nih.gov/39002014/
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