卵巢癌是女性生殖器官最常見(jiàn)的惡性腫瘤之一,是婦科惡性腫瘤的主要死亡原因,晚期5年生存率不到42%。近年來(lái),基于納米顆粒的治療平臺(tái)出現(xiàn),給卵巢癌患者帶來(lái)了新的希望。然而,未經(jīng)修飾的常規(guī)納米藥物可被網(wǎng)狀內(nèi)皮系統(tǒng)快速清除,導(dǎo)致有限的治療效果。目前研究的一種細(xì)胞膜涂層策略來(lái)賦予納米粒子仿生功能,涂層納米粒子保留了核心成分的物理化學(xué)特性,同時(shí)具有使人工材料擁有難以復(fù)制的復(fù)雜細(xì)胞膜功能。最近,武漢大學(xué)中南醫(yī)院張蔚教授團(tuán)隊(duì)在期刊《ACS nano》(IF:15.881)上發(fā)表了題為”Cancer-Erythrocyte Hybrid Membrane-Camouflaged Magnetic Nanoparticles with Enhanced Photothermal-Immunotherapy for Ovarian Cancer”的文章,將小鼠來(lái)源的ID8卵巢癌細(xì)胞膜與紅細(xì)胞(RBC)膜融合以產(chǎn)生混合仿生涂層(IRM),并制備了混合IRM偽裝的吲哚菁綠(ICG)負(fù)載磁性納米粒子(Fe3O4-ICG@IRM)用于卵巢癌的聯(lián)合治療。Fe3O4-ICG@IRM同時(shí)保留了ID8和RBC細(xì)胞膜蛋白,并在體外和體內(nèi)表現(xiàn)出對(duì)ID8細(xì)胞的高度特異性自我識(shí)別以及延長(zhǎng)的血液循環(huán)壽命。在雙側(cè)腫瘤模型中,IRM包被的納米顆粒也激活了特異性免疫,殺死了同源的ID8腫瘤細(xì)胞,但對(duì)B16-F10腫瘤細(xì)胞沒(méi)有影響。此外,F(xiàn)e3O4-ICG@IRM顯示了協(xié)同光熱治療,通過(guò)光熱誘導(dǎo)的腫瘤壞死導(dǎo)致全細(xì)胞腫瘤抗原的釋放,這通過(guò)激活CD8+細(xì)胞毒性T細(xì)胞和減少調(diào)節(jié)性Foxp3+ T細(xì)胞進(jìn)一步增強(qiáng)了對(duì)原發(fā)性腫瘤和轉(zhuǎn)移性腫瘤的抗腫瘤免疫治療。
本文中使用了欣博盛Mouse IL-1β, IL-6, TNF-α和IFN-γ檢測(cè)了細(xì)胞上清液細(xì)胞因子的表達(dá)量。
1.文章題目:Cancer-Erythrocyte Hybrid Membrane-Camouflaged Magnetic Nanoparticles with Enhanced Photothermal-Immunotherapy for Ovarian Cancer.
期????刊:ACS nano(影響因子:15.881)
發(fā)表時(shí)間:3?December 2021
作????者:Xiong J, Wu M, Chen J, et al.
作者單位:武漢大學(xué)中南醫(yī)院
使用產(chǎn)品:Mouse IL-1β, IL-6, TNF-α and IFN-γ ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/34860006/
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2.文章題目:Mature dendritic cell-derived dendrosomes swallow oxaliplatin-loaded nanoparticles to boost immunogenic chemotherapy and tumor antigen-specific immunotherapy.
期????刊:Bioactive Materials(影響因子:14.593)
發(fā)表時(shí)間:21 December 2021
作????者:Chen X, Ling X, Xia J, et al.
作者單位:復(fù)旦大學(xué)
使用產(chǎn)品:Mouse IL-12p70 and IFN-γ ELISA Kits
樣本類(lèi)型:腫瘤組織
https://www.sciencedirect.com/science/article/pii/S2452199X21005946
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3.文章題目:A bioinspired hierarchical nanoplatform targeting and responding to intracellular pathogens to eradicate parasitic infections.
期????刊:Biomaterials(影響因子:12.479)
發(fā)表時(shí)間:6 December 2021
作????者:Yu Y, Li J, Zhang Y, et al.
作者單位:南開(kāi)大學(xué)??
使用產(chǎn)品:Mouse TNF-α, IL-6 and MCP-1 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/34896862/
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4.文章題目:NR4A1 suppresses pyroptosis by transcriptionally inhibiting NLRP3 and IL-1β and co-localizing with NLRP3 in trans-Golgi to alleviate pathogenic bacteria-induced colitis.
期????刊:Clinical and Translational Medicine(影響因子:11.492)
發(fā)表時(shí)間:19 December 2021
作????者:Deng Z, Yang Z, Cui C, et al.
作者單位:華中農(nóng)業(yè)大學(xué)
使用產(chǎn)品:Mouse?IL-1β and IL-18 ELISA Kits
樣本類(lèi)型:結(jié)腸組織
https://pubmed.ncbi.nlm.nih.gov/34923769/
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5.文章題目:wSDTNBI: a novel network-based inference method for virtual screening.
期????刊:Chemical Science(影響因子:9.825)
發(fā)表時(shí)間:21 December 2021
作????者:Wu Z, Ma H, Liu Z, et al.
作者單位:華東理工大學(xué)
使用產(chǎn)品:Mouse IL-17A ELISA Kit
樣本類(lèi)型:大腦和脊髓組織
https://pubs.rsc.org/en/content/articlehtml/2022/sc/d1sc05613a
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6.文章題目:Artemisinin and Procyanidins loaded multifunctional nanocomplexes alleviate atherosclerosis via simultaneously modulating lipid influx and cholesterol efflux.
期????刊:Journal of Controlled Release(影響因子:9.776)
發(fā)表時(shí)間:21 December 2021
作????者:Zhou H, You P, Liu H, et al.
作者單位:湖南大學(xué)?
使用產(chǎn)品:Mouse MCP-1, TNF-α, IL-1β and IL-6 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/34942304/
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7.文章題目:Structural and inflammatory characteristics of Maillard reaction products from litchi thaumatin-like protein and fructose.
期????刊:Food Chemistry(影響因子:7.514)
發(fā)表時(shí)間:9 December 2021
作????者:Wang K, Li W, Wang K, et al.
作者單位:華南農(nóng)業(yè)大學(xué)
使用產(chǎn)品:Mouse TNF-α, IL-1β and IL-6 ELISA Kits ?????
https://pubmed.ncbi.nlm.nih.gov/34920401/
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8.文章題目:Secretogranin II impairs tumor growth and angiogenesis by promoting degradation of hypoxia-inducible factor-1α?in colorectal cancer.
期????刊:Molecular Oncology(影響因子:6.603)
發(fā)表時(shí)間:December 2021
作????者:Fang C, Dai L, Wang C, et al.
作者單位:四川大學(xué)華西醫(yī)院
使用產(chǎn)品:Human VEGF ELISA Kit
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637574/
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9.文章題目:High-Fat Diet-Induced Fatty Liver Is Associated with Immunosuppressive Response during Sepsis in Mice.
期????刊:Oxidative Medicine and Cellular Longevity(影響因子:6.543)
發(fā)表時(shí)間:8 December 2021
作????者:Wang F, Cen Z, Liu Z, et al.
作者單位:南方醫(yī)科大學(xué)珠江醫(yī)院
使用產(chǎn)品:Mouse TNF-α, IL-6 and IL-10 ELISA Kits ??
https://pubmed.ncbi.nlm.nih.gov/34925696/
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10.文章題目:Amphibian-derived peptide homodimer promotes regeneration of skin wounds.
期????刊:Biomedicine & Pharmacotherapy(影響因子:6.529)
發(fā)表時(shí)間:20 December 2021
作????者:Fu Y, Li C, Li X, et al.
作者單位:昆明醫(yī)科大學(xué)
使用產(chǎn)品:Mouse?TNF-α and IL-6 ELISA Kits ??
https://pubmed.ncbi.nlm.nih.gov/34923337/
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11.文章題目:Immunomodulatory activity of polysaccharides from the mycelium of Aspergillus cristatus, isolated from Fuzhuan brick tea, associated with the regulation of intestinal barrier function and gut microbiota.
期????刊:Food Research International(影響因子:6.475)
發(fā)表時(shí)間:16 December 2021
作????者:Xie Z, Bai Y, Chen G, et al.
作者單位:南京農(nóng)業(yè)大學(xué)
使用產(chǎn)品:Mouse?IL-1β,?TNF-α, IFN-γ and IgA ELISA Kits
https://www.sciencedirect.com/science/article/abs/pii/S0963996921008012
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12.文章題目:High-fat-induced nonalcoholic fatty liver potentiates vulnerability to and the severity of viral hepatitis in a C3H/HeN mouse model.
期????刊:BioFactors(影響因子:6.113)
發(fā)表時(shí)間:18 December 2021
作????者:Wu T, Hu J, Wang X, et al.
作者單位:華中科技大學(xué)同濟(jì)醫(yī)學(xué)院附屬同濟(jì)醫(yī)院
使用產(chǎn)品:Mouse TNF-α, IL-1β, IL-6, IL-17A, IL-10 and IL-22 ELISA Kits
樣本類(lèi)型:肝組織
https://pubmed.ncbi.nlm.nih.gov/34921696/
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13.文章題目:Anti-Inflammatory, Antioxidant, and Antifibrotic Effects of Gingival-Derived MSCs on Bleomycin-Induced Pulmonary Fibrosis in Mice.
期????刊:International Journal of Molecular Sciences(影響因子:5.923)
發(fā)表時(shí)間:22 December 2021
作????者:Wang X, Zhao S, Lai J, et al.
作者單位:北京師范大學(xué)?
使用產(chǎn)品:Mouse IL-1β, IL-8, TNF-α, TGF-β1, MMP-9, IL-10 ELISA Kits
樣本類(lèi)型:支氣管肺泡灌洗液
https://www.mdpi.com/1422-0067/23/1/99
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14.文章題目:LncRNA Malat-1 From MSCs-Derived Extracellular Vesicles Suppresses Inflammation and Cartilage Degradation in Osteoarthritis.
期????刊:Frontiers in Bioengineering and Biotechnology(影響因子:5.89)
發(fā)表時(shí)間:15 December 2021
作????者:Pan C, Huang W, Chen Q, et al.
作者單位:南昌大學(xué)第二附屬醫(yī)院
使用產(chǎn)品:Human IL-6 ELISA Kit ?
https://pubmed.ncbi.nlm.nih.gov/34976968/
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15.文章題目:Bacteria-Targeting Liposomes for Enhanced Delivery of Cinnamaldehyde and Infection Management.
期????刊:International Journal of Pharmaceutics(影響因子:5.875)
發(fā)表時(shí)間:14 December 2021
作????者:Sang N, Jiang L, Wang Z, et al.
作者單位:上海中醫(yī)藥大學(xué)
使用產(chǎn)品:Mouse IL-1β, TNF-α and IL-6 ELISA Kits
https://www.sciencedirect.com/science/article/abs/pii/S0378517321011625
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16.文章題目:Anti-inflammatory and gut microbiota modulatory effects of polysaccharides from Fuzhuan brick tea on colitis in mice induced by dextran sulfate sodium.
期????刊:Food & Function(影響因子:5.396)
發(fā)表時(shí)間:1 December 2021
作????者:Zeng Z, Xie Z, Chen G, et al.
作者單位:南京農(nóng)業(yè)大學(xué)?
使用產(chǎn)品:Mouse IL-6 and TNF-α ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/34932051/
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17.文章題目:Depression of Non-Neuronal Cholinergic System May Play a Role in Co-Occurrence of Subjective Daytime Sleepiness and Hypertension in Patients with Obstructive Sleep Apnea Syndrome.
期????刊:Nature and Science of Sleep(影響因子:5.346)
發(fā)表時(shí)間:14 December 2021
作????者:Meng Z, Sun B, Chen W, et al.
作者單位:南京醫(yī)科大學(xué)附屬淮安第一醫(yī)院
使用產(chǎn)品:Human IL-6 and TNF-α ELISA Kits ??
https://pubmed.ncbi.nlm.nih.gov/34934375/
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18.文章題目:Ketogenic diet ameliorates cognitive impairment and neuroinflammation in a mouse model of Alzheimer’s disease.
期????刊:CNS Neuroscience & Therapeutics(影響因子:5.243)
發(fā)表時(shí)間:10 December 2021
作????者:Xu Y, Jiang C, Wu J, et al.
作者單位:中國(guó)科學(xué)院深圳先進(jìn)技術(shù)研究所
使用產(chǎn)品:Mouse IL-1β and TNF-α ELISA Kits ??
樣本類(lèi)型:大腦組織
https://pubmed.ncbi.nlm.nih.gov/34889516/
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19.文章題目:Fc-Mediated E2-Dimer Subunit Vaccines of Atypical Porcine Pestivirus Induce Efficient Humoral and Cellular Immune Responses in Piglets.
期????刊:Viruses(影響因子:5.048)
發(fā)表時(shí)間:6 December 2021
作????者:Ren X, Qian P, Liu S, et al.
作者單位:華中農(nóng)業(yè)大學(xué)
使用產(chǎn)品:Porcine IFN-γ, IL-2, IL-4 and IL-10 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/34960713/
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20.文章題目:Disulfiram attenuates MCMV-Induced pneumonia by inhibition of NF-κB/NLRP3 signaling pathway in immunocompromised mice.
期????刊:International Immunopharmacology(影響因子:4.932)
發(fā)表時(shí)間:24 December 2021
作????者:Huang X, Sun P, Qin Y, et al.
作者單位:廣州醫(yī)科大學(xué)附屬第五醫(yī)院
使用產(chǎn)品:Mouse IL-1β, TNF-α, MCP-1 and IL-10 ELISA Kits
樣本類(lèi)型:肺組織
https://pubmed.ncbi.nlm.nih.gov/34959186/
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21.文章題目:Migration, Distribution, and Safety Evaluation of Specific Phenotypic and Functional Mouse Spleen-Derived Invariant Natural Killer T2 Cells after Adoptive Infusion.
期????刊:Mediators of Inflammation(影響因子:4.711)
發(fā)表時(shí)間:8 December 2021
作????者:Chen D, Xu W, Teng J, et al. ?
作者單位:河北大學(xué)
使用產(chǎn)品:Mouse IL-17A, TNF-α, IFN-γ and IL-4 ELISA Kits ??
https://pubmed.ncbi.nlm.nih.gov/34924812/
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22.文章題目:H. pylori?CagA activates the NLRP3 inflammasome to promote gastric cancer cell migration and invasion.
期????刊:Inflammation Research(影響因子:4.575)?
發(fā)表時(shí)間:2 December 2021
作????者:Zhang X Y, Li C, Chen D, et al.
作者單位:貴州醫(yī)科大學(xué)
使用產(chǎn)品:Human IL-1β and IL-18 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/34854954/
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23.文章題目:Assessment of Alveolar Bone and Periodontal Status in Peritoneal Dialysis Patients.
期????刊:Frontiers in Physiology(影響因子:4.566)
發(fā)表時(shí)間:13 December 2021
作????者:Sun K, Shen H, Liu Y, et al.
作者單位:上海交通大學(xué)
使用產(chǎn)品:Human IL-1β ELISA Kit
樣本類(lèi)型:齦溝液
https://pubmed.ncbi.nlm.nih.gov/34966288/
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24.文章題目:MMP12 knockout prevents weight and muscle loss in tumor-bearing mice.
期????刊:BMC cancer(影響因子:4.43)?
發(fā)表時(shí)間:4 December 2021
作????者:Jiang L, Yang M, He S, et al.
作者單位:廣東藥科大學(xué)
使用產(chǎn)品:Human IL-6, mouse JE/MCP1/CCL2, IL-6 and KC/IL-8/CXCL1 ELISA Kits ?
https://pubmed.ncbi.nlm.nih.gov/34863141/
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25.文章題目:Hydrogen sulfide attenuates ferroptosis and stimulates autophagy by blocking mTOR signaling in sepsis-induced acute lung injury.
期????刊:Molecular Immunology(影響因子:4.407)
發(fā)表時(shí)間:21 December 2021
作????者:Li J, Li M, Li L, et al.
作者單位:華中科技大學(xué)同濟(jì)醫(yī)學(xué)院附屬協(xié)和醫(yī)院
使用產(chǎn)品:Mouse IL-1β, IL-17?and IL-18 ELISA Kits
https://www.sciencedirect.com/science/article/abs/pii/S0161589021003424
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26.文章題目:The antifibrotic effect of pheretima protein is mediated by the TGF-β1/Smad2/3 pathway and attenuates inflammation in bleomycin-induced idiopathic pulmonary fibrosis.
期????刊:Journal of Ethnopharmacology(影響因子:4.36)
發(fā)表時(shí)間:7 December 2021
作????者:Li S, Yang Q, Chen F, et al.
作者單位:南方醫(yī)科大學(xué)
使用產(chǎn)品:Mouse?TGF-β1 and IL-2 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/34890730/
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27.文章題目:Anti-Inflammatory Activity of Four Triterpenoids Isolated from Poriae Cutis.
期????刊:Foods(影響因子:4.35)
發(fā)表時(shí)間:20 December 2021
作????者:Zhang L, Yin M, Feng X, et al.
作者單位:華中農(nóng)業(yè)大學(xué)
使用產(chǎn)品:Mouse TNF-α, IL-1β and IL-6 ELISA Kits ??
https://pubmed.ncbi.nlm.nih.gov/34945705/
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28.文章題目:Bioactive pentacyclic triterpenoids from the whole plants of Pterocephalus hookeri.
期????刊:Phytochemistry(影響因子:4.072)
發(fā)表時(shí)間:8 December 2021
作????者:Zhang J S, Qian Y, Xin Z Q, et al.
作者單位:濟(jì)南大學(xué)
使用產(chǎn)品:Mouse TNF-α and IL-6 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/34890888/
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29.文章題目:Interleukin-4 activates the PI3K/AKT signaling to promote apoptosis and inhibit the proliferation of granulosa cells.
期????刊:Experimental Cell Research(影響因子:3.905)
發(fā)表時(shí)間:29 December 2021
作????者:Han Y, Yao R, Yang Z, et al.
作者單位:天津市婦產(chǎn)科中心醫(yī)院?
使用產(chǎn)品:Human?IL-1β, IL-4, IL-6 and IL-10 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/34973261/
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30.文章題目:MiR196a-5p in extracellular vesicles released from human nasopharyngeal carcinoma enhance the phagocytosis and secretion of microglia by targeting ROCK1.
期????刊:Experimental Cell Research(影響因子:3.905)
發(fā)表時(shí)間:21 December 2021
作????者:Chen P, Liu R, Yu Z, et al.
作者單位:華中科技大學(xué)同濟(jì)醫(yī)學(xué)院附屬同濟(jì)醫(yī)院
使用產(chǎn)品:Human?TGF-β1, IL-6 and IL-8 ELISA Kits
https://pubmed.ncbi.nlm.nih.gov/34951996/
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31.文章題目:Pitavastatin maintains MAPK7 expression and alleviates angiotensin II?induced vascular endothelial cell inflammation and injury.
期????刊:Experimental and Therapeutic Medicine(影響因子:2.447)
發(fā)表時(shí)間:13?December 2021
作????者:Li M, Liu X.
作者單位:浙江大學(xué)醫(yī)學(xué)院附屬第二醫(yī)院
使用產(chǎn)品:Human?IL-1β ELISA Kit
https://www.spandidos-publications.com/10.3892/etm.2021.11055
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32.文章題目:Analysis of pathogenic factors of Candida albicans and the effect of vaginal immunization on recurrent vulvovaginal candidiasis in mice.
期????刊:Journal of Obstetrics and Gynaecology Research(影響因子:1.73)
發(fā)表時(shí)間:30 December 2021
作????者:Shao M K, Qi W J, Hou M Y, et al.
作者單位:昆明醫(yī)科大學(xué)第二附屬醫(yī)院
使用產(chǎn)品:Mouse IL-4,?IL-8 and?IL-17 ELISA Kits
樣本類(lèi)型:陰道灌洗液
https://pubmed.ncbi.nlm.nih.gov/34970814/
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